近年来，获得医疗保健监管批准的机器学习（ML）技术的数量已大大增加，从而使其可以投入市场。但是，与ML的数据驱动和学习的行为相比，最初是为传统软件设计了用于它们的监管框架。由于框架正在改革的过程中，因此有必要主动确保ML的安全以防止患者的安全受到损害。在自主系统（AMLAS）方法中使用的机器学习的保证是由基于系统安全性良好概念的Assunity International计划开发的。这篇综述通过咨询ML制造商了解该方法是否融合或与其当前安全保证实践有所不同，是否存在差距和限制，是否有差距和局限性，以及当应用于医疗保健领域时是否适合目的。通过这项工作，我们认为，当应用于医疗机器学习技术时，AMLAS是一种安全保证方法，尽管医疗保健特定的补充指导的开发将使实施该方法论的人受益。

保证案件提出了一个明确且可辩护的论点，并得到证据支持，即系统将按照特定情况下的意图运行。通常，保证案例提出了一个论点，即系统在其预期的上下文中将是安全的。值得信赖的AI研究社区中的一项新兴建议是扩展和应用这种方法，以保证使用AI系统或自治系统（AI/AS）在特定情况下将是可接受的道德。在本文中，我们进一步提出了这一建议。我们通过为AI/AS提供基于原则的道德保证（PBEA）论点模式来做到这一点。 PBEA参数模式为推理给定AI/AS的整体道德可接受性提供了一个框架，它可能是特定道德保证案例的早期原型模板。构成PBEA论证模式基础的四个核心道德原则是：正义；福利；非遗憾；并尊重个人自主权。在整个过程中，我们将参数模式的阶段连接到AI/作为应用程序的示例。这有助于显示其最初的合理性。

The field of autonomous mobile robots has undergone dramatic advancements over the past decades. Despite achieving important milestones, several challenges are yet to be addressed. Aggregating the achievements of the robotic community as survey papers is vital to keep the track of current state-of-the-art and the challenges that must be tackled in the future. This paper tries to provide a comprehensive review of autonomous mobile robots covering topics such as sensor types, mobile robot platforms, simulation tools, path planning and following, sensor fusion methods, obstacle avoidance, and SLAM. The urge to present a survey paper is twofold. First, autonomous navigation field evolves fast so writing survey papers regularly is crucial to keep the research community well-aware of the current status of this field. Second, deep learning methods have revolutionized many fields including autonomous navigation. Therefore, it is necessary to give an appropriate treatment of the role of deep learning in autonomous navigation as well which is covered in this paper. Future works and research gaps will also be discussed.

Multi-class ensemble classification remains a popular focus of investigation within the research community. The popularization of cloud services has sped up their adoption due to the ease of deploying large-scale machine-learning models. It has also drawn the attention of the industrial sector because of its ability to identify common problems in production. However, there are challenges to conform an ensemble classifier, namely a proper selection and effective training of the pool of classifiers, the definition of a proper architecture for multi-class classification, and uncertainty quantification of the ensemble classifier. The robustness and effectiveness of the ensemble classifier lie in the selection of the pool of classifiers, as well as in the learning process. Hence, the selection and the training procedure of the pool of classifiers play a crucial role. An (ensemble) classifier learns to detect the classes that were used during the supervised training. However, when injecting data with unknown conditions, the trained classifier will intend to predict the classes learned during the training. To this end, the uncertainty of the individual and ensemble classifier could be used to assess the learning capability. We present a novel approach for novel detection using ensemble classification and evidence theory. A pool selection strategy is presented to build a solid ensemble classifier. We present an architecture for multi-class ensemble classification and an approach to quantify the uncertainty of the individual classifiers and the ensemble classifier. We use uncertainty for the anomaly detection approach. Finally, we use the benchmark Tennessee Eastman to perform experiments to test the ensemble classifier's prediction and anomaly detection capabilities.

We address the problem of unsupervised domain adaptation when the source domain differs from the target domain because of a shift in the distribution of a latent subgroup. When this subgroup confounds all observed data, neither covariate shift nor label shift assumptions apply. We show that the optimal target predictor can be non-parametrically identified with the help of concept and proxy variables available only in the source domain, and unlabeled data from the target. The identification results are constructive, immediately suggesting an algorithm for estimating the optimal predictor in the target. For continuous observations, when this algorithm becomes impractical, we propose a latent variable model specific to the data generation process at hand. We show how the approach degrades as the size of the shift changes, and verify that it outperforms both covariate and label shift adjustment.

In intensively managed forests in Europe, where forests are divided into stands of small size and may show heterogeneity within stands, a high spatial resolution (10 - 20 meters) is arguably needed to capture the differences in canopy height. In this work, we developed a deep learning model based on multi-stream remote sensing measurements to create a high-resolution canopy height map over the "Landes de Gascogne" forest in France, a large maritime pine plantation of 13,000 km$^2$ with flat terrain and intensive management. This area is characterized by even-aged and mono-specific stands, of a typical length of a few hundred meters, harvested every 35 to 50 years. Our deep learning U-Net model uses multi-band images from Sentinel-1 and Sentinel-2 with composite time averages as input to predict tree height derived from GEDI waveforms. The evaluation is performed with external validation data from forest inventory plots and a stereo 3D reconstruction model based on Skysat imagery available at specific locations. We trained seven different U-net models based on a combination of Sentinel-1 and Sentinel-2 bands to evaluate the importance of each instrument in the dominant height retrieval. The model outputs allow us to generate a 10 m resolution canopy height map of the whole "Landes de Gascogne" forest area for 2020 with a mean absolute error of 2.02 m on the Test dataset. The best predictions were obtained using all available satellite layers from Sentinel-1 and Sentinel-2 but using only one satellite source also provided good predictions. For all validation datasets in coniferous forests, our model showed better metrics than previous canopy height models available in the same region.

Cancer is one of the most challenging diseases because of its complexity, variability, and diversity of causes. It has been one of the major research topics over the past decades, yet it is still poorly understood. To this end, multifaceted therapeutic frameworks are indispensable. \emph{Anticancer peptides} (ACPs) are the most promising treatment option, but their large-scale identification and synthesis require reliable prediction methods, which is still a problem. In this paper, we present an intuitive classification strategy that differs from the traditional \emph{black box} method and is based on the well-known statistical theory of \emph{sparse-representation classification} (SRC). Specifically, we create over-complete dictionary matrices by embedding the \emph{composition of the K-spaced amino acid pairs} (CKSAAP). Unlike the traditional SRC frameworks, we use an efficient \emph{matching pursuit} solver instead of the computationally expensive \emph{basis pursuit} solver in this strategy. Furthermore, the \emph{kernel principal component analysis} (KPCA) is employed to cope with non-linearity and dimension reduction of the feature space whereas the \emph{synthetic minority oversampling technique} (SMOTE) is used to balance the dictionary. The proposed method is evaluated on two benchmark datasets for well-known statistical parameters and is found to outperform the existing methods. The results show the highest sensitivity with the most balanced accuracy, which might be beneficial in understanding structural and chemical aspects and developing new ACPs. The Google-Colab implementation of the proposed method is available at the author's GitHub page (\href{https://github.com/ehtisham-Fazal/ACP-Kernel-SRC}{https://github.com/ehtisham-fazal/ACP-Kernel-SRC}).

Fisher's criterion is a widely used tool in machine learning for feature selection. For large search spaces, Fisher's criterion can provide a scalable solution to select features. A challenging limitation of Fisher's criterion, however, is that it performs poorly when mean values of class-conditional distributions are close to each other. Motivated by this challenge, we propose an extension of Fisher's criterion to overcome this limitation. The proposed extension utilizes the available heteroscedasticity of class-conditional distributions to distinguish one class from another. Additionally, we describe how our theoretical results can be casted into a neural network framework, and conduct a proof-of-concept experiment to demonstrate the viability of our approach to solve classification problems.

Vision Transformers convert images to sequences by slicing them into patches. The size of these patches controls a speed/accuracy tradeoff, with smaller patches leading to higher accuracy at greater computational cost, but changing the patch size typically requires retraining the model. In this paper, we demonstrate that simply randomizing the patch size at training time leads to a single set of weights that performs well across a wide range of patch sizes, making it possible to tailor the model to different compute budgets at deployment time. We extensively evaluate the resulting model, which we call FlexiViT, on a wide range of tasks, including classification, image-text retrieval, open-world detection, panoptic segmentation, and semantic segmentation, concluding that it usually matches, and sometimes outperforms, standard ViT models trained at a single patch size in an otherwise identical setup. Hence, FlexiViT training is a simple drop-in improvement for ViT that makes it easy to add compute-adaptive capabilities to most models relying on a ViT backbone architecture. Code and pre-trained models are available at https://github.com/google-research/big_vision

Adequate strategizing of agents behaviors is essential to solving cooperative MARL problems. One intuitively beneficial yet uncommon method in this domain is predicting agents future behaviors and planning accordingly. Leveraging this point, we propose a two-level hierarchical architecture that combines a novel information-theoretic objective with a trajectory prediction model to learn a strategy. To this end, we introduce a latent policy that learns two types of latent strategies: individual $z_A$, and relational $z_R$ using a modified Graph Attention Network module to extract interaction features. We encourage each agent to behave according to the strategy by conditioning its local $Q$ functions on $z_A$, and we further equip agents with a shared $Q$ function that conditions on $z_R$. Additionally, we introduce two regularizers to allow predicted trajectories to be accurate and rewarding. Empirical results on Google Research Football (GRF) and StarCraft (SC) II micromanagement tasks show that our method establishes a new state of the art being, to the best of our knowledge, the first MARL algorithm to solve all super hard SC II scenarios as well as the GRF full game with a win rate higher than $95\%$, thus outperforming all existing methods. Videos and brief overview of the methods and results are available at: https://sites.google.com/view/hier-strats-marl/home.